Epigenetic Regulation of Mammalian Stem Cells
نویسندگان
چکیده
منابع مشابه
Epigenetic regulation of mammalian stem cells.
Two critical properties of stem cells are self-renewal and multipotency. The maintenance of their "stemness" state and commitment to differentiation are therefore tightly controlled by intricate molecular networks. Epigenetic mechanisms, including DNA methylation, chromatin remodeling and the noncoding RNA-mediated process, have profound regulatory roles in mammalian gene expression. Recent stu...
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1Department of Biosciences, University of Milan, 20133 Milan, Italy 2IRCCS Fondazione Santa Lucia, 00143 Rome, Italy 3National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892-8022, USA 4Institute of Translational Pharmacology, National Research Council (CNR), 00133 Rome, Italy 5Stem Cell Metabolism & Regenerative Medicine Group, Ba...
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ژورنال
عنوان ژورنال: Stem Cells and Development
سال: 2008
ISSN: 1547-3287,1557-8534
DOI: 10.1089/scd.2008.0036